The United States spent, adjusted for inflation, a quarter trillion dollars on the Apollo project. The most famous of the astronauts who reached the lunar surface, Neil Armstrong, later suffered such severe depression that he was deposited in a psych ward. I have no doubt that he found that more frightening than his expedition into outer space, and granted how many more people will make the journey to and from despair, it’s surprising that more effort hasn’t been expended understanding the science behind it.