What did they know, and when did they know it? That is, when did the Sackler family know that OxyContin, the drug responsible for their vast fortune, was also partly responsible for the opioid crisis? Such questions are no abstraction to the family of billionaires currently fending off some 3,000 lawsuits filed by nearly every state, as well as many cities, counties, and tribal governments, in America. The lawsuits allege, among other crimes, that the privately owned Sackler family business, Purdue Pharma, downplayed the risks of its blockbuster drug while illegally boosting its sales, and that this scheme to profit led to unfathomable destruction.